Basophil

Saturday, September 26, 2009

A basophil is a type of Leukocyte which is characterized by granules in its cytoplasm. Ganules-containing leukocytes are called granulocytes. Basophils secrete a biologically active substance such as histamine and proteoglycans. Basophils show up in specific types of inflammatory reactions, specially those which trigger allergic symptoms. Basophils produce anticoagulant heparin, which prevents blood from clotting too quickly.

A basophil measures between 12 and 15 microns in diameter. A basophile mature nucleus has 2 or 3 lobes. Basophils are produced by stem cells in the bone marrow. Their function is to phagocytate foreign particles and produce heparin and histamine.