Myofibrillar degeneration

Friday, August 16, 2013

Myofibrillar degeneration is a heart condition characterized by a series of lesions scattered throughout the myocardium (heart muscle) or a lesion surrounding infarcts necrosis. Under the electronic microscope, dense clusters of damaged myofilaments can be seen, with felt-like splitting of myofibrils. These alterations of the myocardium organization can be spotted using staining methods. Myofibrillar degeneration can be caused by, or is associated with, raised intracranial pressure, heart surgery, and intense stress.