Hemochromatosis

Thursday, June 25, 2015

The hemochromatosis is a hereditary disease, which is characterized by the abnormal deposit of a great quantity of iron in all the body organs, mainly in the form of hemosiderin (an iron-containing protein). Along with the iron build-up, there is also an excessive accumulation of hemofuscin, which is a brownish yellow hematogenous pigment. This abnormal amount of iron is specially found in the reticuloendothelial system but also in the parenchyma of the liver, panchreas, and other organs, causing a secondary fibrosis. The main consequence of hemochromatosis is liver cirrhosis and death, if the patient does not receive a liver transplant.