Monday, March 2, 2009


Streptomycin is a bactericidal antibiotic which belongs to aminoglycoside group of antibiotics. It was the first to be discovered and the first remedy for tuberculosis. Streptomycin is derived from the actinobacterium Streptomyces griseus. It kills sensitive microbes by inhibiting protein synthesis. More specifically, it binds to the 16S rRNA of the bacterial ribosome and interferes with the binding of formyl-methionyl-tRNA to the 30S subunit.

Streptomycin is a water-soluble aminoglycoside. The chemical name of streptomycin sulfate is D-Streptamine.