The Schlemm's canal is a space at the junction of the sclera and cornea in the eye. It drains aqueous humor from the anterior chamber of the eye and delivers it into the anterior ciliary veins. The Schlemm's canal is an endothelium-lined tube, that resembles that of a lymphatic vessel. On the inside, it is covered by the trabecular meshwork; this region makes the greatest contribution to outflow resistance of the aqueous humor.
The Schlemm's canal drains approximately 2-3 microliters of aqueous humor per minute. If debris builds up, due to infection in the aqueous humor, the canal is blocked, making the intraocular pressure go up, which causes glaucoma.